ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,467,040, issued on Nov. 11, was assigned to ABclonal Science Inc. (Woburn, Mass.).
"Mutant Taq polymerase for increased salt concentration or body fluids" was invented by Zhenyu Zhu (Lynnfield, Mass.), Dapeng Sun (Lexington, Mass.) and Weiling Peng (Farmington, Conn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention includes a mutant Taq polymerase, which can effectively amplify a target sequence under conditions of salt concentration(s) similar to body fluids, including blood, serum or plasma preserved with sodium citrate. The mutant Taq polymerase, or a biologically active fragment thereof, has one or more substitutions differing from the w...