US Patent Issued to ABCLON on Sept. 16 for "Anti-HER2 affibody and switchable chimeric antigen receptor using same as switch molecule" (South Korean Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,414,998, issued on Sept. 16, was assigned to ABCLON INC. (Seoul, South Korea).

"Anti-HER2 affibody and switchable chimeric antigen receptor using same as switch molecule" was invented by Ki Hyun Kim (Seoul, South Korea), Hyun-Jong Lee (Incheon, South Korea) and Jong-Seo Lee (Gyeonggi-do, South Korea).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are an anti-HER2 affibody and a switch molecule including a cotinine-conjugated anti-HER2 affibody. When applied in combination with Cot-sCART, the cotinine-conjugated anti-HER2 affibody reacts with HER2-positive cells to induce immune cell activity, thereby finding advantageous applications as...