ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,433,855, issued on Oct. 7, was assigned to AALTO UNIVERSITY FOUNDATION SR (Aalto, Finland).

"Method of inhibiting gram-negative bacterial quorum signalling molecules using the macrocycle pillar[5arene" was invented by Christopher Jonkergouw (Aalto, Finland), Kodiah Beyeh (Aalto, Finland), Ekaterina Osmekhina (Aalto, Finland), Robin Ras (Aalto, Finland) and Markus Linder (Aalto, Finland).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to macrocyclic cavity containing compounds and uses thereof in inhibiting a microbial signalling molecule or in reducing the amount of a microbial signalling molecule in a subject. The invention also rel...