US Patent Issued to 858 THERAPEUTICS on Oct. 7 for "Substituted imidazo[1,2-Aquinazolines as inhibitors of PARG" (California Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,092, issued on Oct. 7, was assigned to 858 THERAPEUTICS INC. (San Diego).

"Substituted imidazo[1,2-Aquinazolines as inhibitors of PARG" was invented by James M. Veal (Solana Beach, Calif.), Jeffrey A. Stafford (Rancho Santa Fe, Calif.), Donald S. Karanewsky (Escondido, Calif.) and Shyama Herath (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are inhibitors of PARG, pharmaceutical compositions comprising the inhibitory compounds, and methods for using the PARG inhibitory compounds for the treatment of disease. Said inhibitors of PARG have the structure provided in Formula (I):"

The patent was filed on Feb. 14, 2024, under Ap...