US Patent Issued to 10x Genomics on June 3 for "Methods and systems for targeted RNA cleavage and target RNA-primed rolling circle amplification" (California Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,956, issued on June 3, was assigned to 10x Genomics Inc. (Pleasanton, Calif.).

"Methods and systems for targeted RNA cleavage and target RNA-primed rolling circle amplification" was invented by Su Wang (Berkeley, Calif.) and Robert Henley (Castro Valley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates in some aspects to methods, systems, and kits for analyzing a biological sample comprising generating a rolling circle amplification product (RCP) using a target ribonucleic acid (RNA) as a primer. In some aspects, RNase H and a nucleic acid oligonucleotide are used to generate a free 3' end of the target RNA to prim...