US Patent Issued to 10X GENOMICS on July 22 for "Compositions and methods for amplification and sequencing" (California Inventors)

ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,944, issued on July 22, was assigned to 10X GENOMICS INC. (Pleasanton, Calif.).

"Compositions and methods for amplification and sequencing" was invented by Patrick J. Marks (San Francisco) and Michael Schnall-Levin (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions for performing a rolling circle amplification (RCA) reaction using circularized template comprising identifier sequences are provided. Sequencing is performed on the RCA product using a polymerase to incorporate a plurality of cognate nucleotides into the sequencing primer or an extension product thereof to generate an extension product."

The patent wa...