US Patent Issued to 10x Genomics on April 29 for "Increasing efficiency of spatial analysis in a biological sample" (Italian Inventor)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,673, issued on April 29, was assigned to 10x Genomics Inc. (Pleasanton, Calif.).

"Increasing efficiency of spatial analysis in a biological sample" was invented by Felice Alessio Bava (Rome).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods of amplifying an analyte in a biological sample using a bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed herein include steps of (a) contacting a biological sample with a substrate having capture probes comprising a capture domain and a spatial barcode; (b) hybridizing the analyte to the capture domain; and (c) contacting the analyte to a bridging oligo...