ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,623, issued on Oct. 21.
"siRNA specifically binding to M2 macrophage CD206 and application thereof" was invented by Gang Niu (Beijing) and Huanran Tan (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "An siRNA specifically binding to M2 macrophage CD206 is provided, which is at least one of siRNA-1, siRNA-2, and siRNA-3, or at least one of siRNA-4, siRNA-5, and siRNA-6. The siRNA specifically combined with CD206 of the M2 macrophage reduces the expression of CD206 by specifically binding to CD206 of the macrophage, thereby promoting the proliferation of the M2 macrophage and further inhibiting the proliferation and migration of tumor cells."
...