ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,447,215, issued on Oct. 21.

"Nanoparticle probes and methods of making and use thereof" was invented by Paul C. Lee (Columbia, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Some embodiments relate to nanoparticle probes for the detection of disease states in a patient or for tissue engineering. In some embodiments, the nanoparticle probe comprises one or more slip bonds that bind to a cell surface structure. In some embodiments, the binding of the nanoparticle probe is selective. In some embodiments, the nanoparticle probe binds to cells having a certain maximum glycocalyx thickness."

The patent was filed on June 20, 2023, under Application No. 18...