ALEXANDRIA, Va., Nov. 6 -- United States Patent no. 12,458,535, issued on Nov. 4.
"Endothelial-integrated stent for Schlemm's canal and controlled aqueous humor outflow" was invented by Michael Reynard (Santa Monica, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A bioengineered endothelial stent designed for implantation in Schlemm's canal enhances aqueous humor outflow and restores physiological intraocular pressure regulation. Unlike conventional devices, this stent integrates transplanted Schlemm's canal endothelial cells (SCECs) to restore mechanosensitive outflow regulation. The stent features a biocompatible or biodegradable scaffold with an endothelial cell-seeding system to support integratio...