ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,474,350, issued on Nov. 18.
"Low energy cleavable mass tag for quantitative proteomics" was invented by Felix Meissner (Berlin), Matthias Mann (Munich), Florian Meier (Pullach, Germany), Sebastian Virreira Winter (Munich) and Arturo Zychlinsky (Berlin).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a compound which comprises or consists of (a) a reactive moiety, said reactive moiety being capable of reacting with a functional group of a peptide to form a covalent bond; and covalently joined thereto (b) a moiety which fragments in the mass spectrometer (i) at an energy below the energy required for fragmenting peptides and...