ALEXANDRIA, Va., June 10 -- United States Patent no. 12,290,528, issued on May 6.

"Compositions and methods for treatment of sepsis-related disorders" was invented by John Mansell (Gillette, Wyo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method comprising administering, to a subject in need thereof, an effective amount of a nucleotide effective to disrupt one or more pathways leading to sepsis. The nucleotide may be a nitric oxide disruptor effective to decrease the expression of inducible nitric oxide synthase. The nitric oxide disrupter may comprise a polynucleotide strand exhibiting at least 70% sequence identity to one of Sequence ID No. 1 through Sequence ID No. 47. Additionally or alternatively,...