ALEXANDRIA, Va., June 25 -- United States Patent no. 12,336,993, issued on June 24.
"Therapeutic benefit of suboptimally administered chemical compounds" was invented by Dennis M. Brown (Menlo Park, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention describes methods and compositions for improving the therapeutic efficacy of therapeutic agents previously limited by suboptimal therapeutic performance by either improving efficacy as monotherapy or reducing side effects. Such methods and compositions are particularly applicable to mustard-based alkylating agents such as uracil mustard and analogs, derivatives, or prodrugs thereof, including 6-methyluracil mustard and 6-ethyluracil musta...