ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,069, issued on July 15.

"Azacyanine dyes and use thereof" was invented by Riccardo Sinisi (Lausanne, Switzerland), Alma Rosa Morales Morales (Lausanne, Switzerland), Elena A. Goun (Lausanne, Switzerland), Rajendra Singh (Lausanne, Switzerland) and Pavlo Khodakivskyi (Columbia, Mo.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The application provides fluorescent dyes, which are cyanine dyes that incorporate additional aza moieties in the indolenium heterocycles and/or in the methine chains connecting them. Symmetrical and unsymmetrical chemically reactive azacyanine dyes are described for conjugation, as well as their bioconjugates for in-vitro and...