US Patent Issued on July 1 for "Amelioration and treatment of infarction damage with a polypeptide segement of BNIP3" (German Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,644, issued on July 1.

"Amelioration and treatment of infarction damage with a polypeptide segement of BNIP3" was invented by Tienush Rassaf (Essen, Germany) and Ulrike Hendgen-Cotta (Dinslaken, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "Infarction damage is ameliorated or treated through the administration of a mitochondrial degradation inhibitor, such as one that acts by inhibiting translocation of one or more molecules across a mitochondrial membrane, for example BAX/BNIP3 complexes involved in mitochondrial degradation. By preventing mitochondrial degradation, one allows more efficient oxygenation of an infarcted region, allowing for ...