US Patent Issued on Feb. 3 for "Arterial application of low dose ethyl alcohol enables blood-brain barrier (BBB) transient opening" (California Inventor)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,539,281, issued on Feb. 3.

"Arterial application of low dose ethyl alcohol enables blood-brain barrier (BBB) transient opening" was invented by Weijun Wang (San Gabriel, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of inducing blood-brain barrier (BBB) opening for delivery of a non-BBB permeable substance to a brain of a subject includes the steps of: administering an ethyl alcohol at 0.01%-5% v/v and the non-BBB permeable substance via microcatheter to a target area of the brain leading from an intracerebral artery and inducing a homogeneous distribution of the non-BBB permeable substance in the target area. The ethyl alcohol reaches t...