ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,248, issued on Dec. 9.
"Method for generating immunoregulatory cells in a blood-derived sample" was invented by Robert Zeiser (Freiburg, Germany), Petya Apostolova (Freiburg, Germany) and Justus Duyster (Freiburg, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method comprising the steps of provision of a sample derived from a blood sample of a subject that has received a checkpoint-inhibitor therapy and is suspected of developing or has developed symptoms of immune-related adverse events (irAE), adding a photosensitizing agent to the sample, and subjecting the sample to irradiation, which preferably generat...