ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,420, issued on Dec. 9.

"Compositions, kits, and methods for in vitro transcription" was invented by Dillon B. Nye (Somerville, Mass.), Jennifer L. Curcuru (Gloucester, Mass.), Tien-Hao Chen (Wakefield, Mass.), Lili Mitchell (Ipswich, Mass.) and Ivan R. Correa Jr. (Hamilton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates, according to some embodiments, to cold-active RNA polymerases, variants thereof, compositions and kits comprising cold-active RNA polymerases, and methods of using cold-active RNA polymerases. Cold-active polymerases may have, for example, an amino acid sequence less than=90%, less than=91%, less ...