ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,939, issued on Aug. 19.

"Genetically-encoded bicyclic peptide libraries" was invented by Ratmir Derda (Edmonton, Canada), Raja Mukherjee (Edmonton, Canada) and Vivian Triana (Edmonton, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a bicyclic peptide complex comprising a peptide construct, said construct comprising (i) a polypeptide with free terminus (N or C); (ii) optionally, a nucleic acid encoding the polypeptide; (iii) a twofold-symmetric linker (TSL) compound attached to said polypeptide where the linker is attached to the terminus of polypeptide via a covalent bond and to at least two discrete side chains of th...