ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,385,066, issued on Aug. 12.
"Retroviral transduction using poloxamers" was invented by Natasa Anastasov (Munich), Ines Hofig (Munich) and Christian Thirion (Munich).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for transducing a target cell, the method comprising the step of contacting a target cell with a retroviral vector and a poloxamer having a molecular weight of 12.8 kDa to about 15 kDa. Further, the invention relates to the use of a poloxamer as defined herein, optionally in combination with a polycationic substance as defined herein, for transducing a target cell with a retroviral vector and a kit compri...