ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,383,550, issued on Aug. 12.
"Opioid overdose reversal mixtures" was invented by John Abernethy (Gainesville, Fla.), Georgiy Nikonov (Gainesville, Fla.) and Michael Voronkov (Somerville, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention presented is a remedial opioid overdose mixture that includes a therapeutically effective dose of an opioid receptor antagonist; and, a therapeutically effective dose of an opioid receptor agonist. In one embodiment, the opioid receptor antagonist is naloxone while the opioid receptor agonist is nalbuphine. One specific naloxone derivative is NX-90 and a specific nalbuphine derivative is NB-33. The mixtur...