US Patent Issued on April 29 for "Cardiosphere-derived cell sheet and methods of making and using the same" (Japanese Inventor)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,644, issued on April 29.

"Cardiosphere-derived cell sheet and methods of making and using the same" was invented by Gen Suzuki (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of making a cell sheet comprising secondary spheroids, including (a) obtaining cardiosphere-derived cells; (b) cultivating the cardiosphere-derived cells for a first period of time in a first media comprising at least one of an ascorbic acid and an analog thereof, to form secondary spheroids; (c) transferring an amount of the spheroids formed in step (b) into a mold; (d) culturing the secondary spheroids for a second period of time in a second media comprising at ...