ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,179, issued on April 22.
"Solution phase synthesis of Beta-turn peptidomimetic cyclic salts" was invented by Sebastien Rocchi (Hoenheim, France), Chantal Devin (Lingolsheim, France), Wei Tian (Sodertalje, Sweden) and Martin Bohlin (Johanneshov, Sweden).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to methods of preparing and crystallizing Beta-turn cyclic peptidomimetic salts of formula I:where R1, R2, R3, R4, R5, R6, R7, R8, R10, X, Y and n are as defined in the specification.The present disclosure provides a more efficient route for preparing a crystalline form of a Beta-turn cyclic peptidomimetic compounds and salts ...