ALEXANDRIA, Va., April 2 -- United States Patent no. 12,265,031, issued on April 1.
"Systems and methods for the detection and analysis of free thiol" was invented by James McElroy (San Jose, Calif.) and Christopher Heger (Campbell, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments described herein relate to devices, and methods for quantifying thiol content in a sample containing a mixture of proteins or protein isoforms. The method includes conjugating a portion of the sample with free thiol detection binders, separating the contents in the portion of the sample into separated protein isoforms, detecting fluorescence signals associated with each separated protein isoform, and quantifying, b...