Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115708) titled 'Oliceridine Combined with Esketamine Improves Analgesic Efficacy and Safety in Elderly Patients After Laparoscopic Colorectal Cancer Surgery: A Randomized Controlled Study' on Dec. 30, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Henan University Huaihe Hospital

Condition: colorectal cancer

Intervention: Oliceridine Group (Group O):Patient-controlled intravenous analgesia (PCIA) with oliceridine alone. The PCIA solution contains oliceridine 20 mg diluted in normal saline to 100 mL. The pump is set with a background infusion of 2 mL/h, a bolus dose of 0.5 mL (oliceridine 0....