International Clinical Trial: Glumetinib combined with platinum-based chemotherapy for the treatment of MET-overexpressing locally advanced or metastatic non-small cell lung cancer: A single-arm, multicenter study

Geneva, Feb. 2 -- International Clinical Trials Registry received information related to the study (ChiCTR2600117342) titled 'Glumetinib combined with platinum-based chemotherapy for the treatment of MET-overexpressing locally advanced or metastatic non-small cell lung cancer: A single-arm, multicenter study' on Jan. 22.

Study Type: Interventional study

Study Design: Single arm

Primary Sponsor: West China Hospital of Sichuan University

Condition: non-small cell lung cancer

Intervention: (Stage Ia)z:Gumetininib: Level 1: 200 mg, day 1 Level 2: 250 mg, day 1 Level 3: 300 mg, day 1 Pemetrexed: 500 mg/m^2, day 1 Carboplatin: AUC=5, day 1 Experimental group (Stage Ib):Gumetinib: Determine the phase Ib dose level based on the results of...