Geneva, May 20 -- International Clinical Trials Registry received information related to the study (NCT06959771) titled 'Base Editing Hematopoietic Stem Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study' on May 6.

Study Type: Interventional

Study Design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Condition: CD40L-HyperIgM Syndrome

Intervention: Drug: Busulfan Drug: Palifermin Drug: Sirolimus Drug: Alemtuzumab

Recruitment Status: Recruiting

Phase: Phase 1/Phase 2

Date of First Enrollment: May 14, 2025

Target Sample Size: 1

Countries of Recruitment: Unite...