U.S., Feb. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07424846) titled 'Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial' on Feb. 14.
Brief Summary: The ground-breaking Prevention of Prematurity and Xylitol (PPaX) cluster randomized controlled clinical trial was conducted in Lilongwe, Malawi and enrolled approximately 10,069 pregnant individuals seeking to evaluate the impact of xylitol-containing chewing gum compared to no chewing gum on reducing the occurrence of maternal periodontal disease, preterm birth, and low birthweight offspring. The premise of this study centers upon the numerous publications supporting a strong association between maternal periodontal disease and pre...