U.S., July 26 -- ClinicalTrials.gov registry received information related to the study (NCT07086820) titled 'Window Prophylaxis for Pediatric Tuberculosis Prevention Trial' on July 17.
Brief Summary: The goal of this cluster-randomized controlled trial is to evaluate the effectiveness of tuberculosis preventive treatment (TPT) administered during the "window period" to prevent new Mycobacterium tuberculosis infections in children and adolescents.
The main question it aims to answer is:
Can immediate TPT reduce the incidence of IGRA conversions in children and adolescents who are household contacts of a newly diagnosed pulmonary tuberculosis patient?
Researchers will compare the incidence of new tuberculosis infections-measured by IGRA c...