U.S., Feb. 11 -- ClinicalTrials.gov registry received information related to the study (NCT07398924) titled 'Vaginal Estradiol and Oral Guaifenesin in Clomiphene Ovulation Induction' on Jan. 26.
Brief Summary: Clomiphene citrate is commonly used for ovulation induction; however, it may negatively affect endometrial development and cervical mucus quality, which can reduce pregnancy rates. Various adjunctive treatments have been proposed to overcome these antiestrogenic effects.
This randomized clinical trial aimed to compare the effects of vaginal estradiol and oral guaifenesin, alone or in combination, on endometrial thickness, cervical mucus characteristics, and clinical pregnancy rates in women undergoing ovulation induction with clomip...