U.S., Feb. 15 -- ClinicalTrials.gov registry received information related to the study (NCT06827041) titled 'Use of Phage Therapy for Treatment of a Periprosthetic Joint Infection' on April 03, 2024.
Brief Summary: The goal of this clinical trial is to learn about the safety, tolerability and activity or efficacy of systemic intravenous and intraarticular administration of a mono-bacteriophage (phage) peparation in a patient with chronic-recalcitrant methicillin-resistant Staphylococcus epidermidis (MRSE) periprosthetic joint infection (PJI) and also to understand clinical changes pre- and post-therapy, as well as identifying adjunctive changes in biomarkers (C-reactive protein [CRP], erythrocyte sedimentation rate [ESR], and interleukin-6...