U.S., Feb. 8 -- ClinicalTrials.gov registry received information related to the study (NCT06814899) titled 'Use of Fosfomycin in the Treatment of Bacterial Infections' on May 20, 2024.
Brief Summary: Fosfomycin is an antibiotic discovered since 1969. Disodium fosfomycin, for intravenous use (C3H5Na2O4P) is a bactericidal antibiotic, available in Italy since 2019 (AIFA approval). It works by blocking the enzyme UDP-N-acetylglucosamine enolpyruvil transferase, inhibiting the synthesis of peptidoglycan. It binds poorly to plasma proteins and is distributed very well in various tissues such as: eyes, bones, skin and subcutaneous tissue, muscles, lungs, prostate, bile and inflamed meninges. It also has a strong anti-biofilm activity.
Fosfomyci...