U.S., Jan. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07360756) titled 'Ultrasonographic ONSD as a Predictor of PDPH in Spinal Anesthesia for Cesarean Delivery' on Dec. 26, 2025.

Brief Summary: The Optic Nerve Sheath Diameter (ONSD), measured non-invasively by bedside ultrasound, is a well-established surrogate for intracranial pressure (ICP), as the optic nerve sheath is continuous with the intracranial dura mater and its subarachnoid space is filled with cerebrospinal fluid (CSF). While ONSD is typically used to detect elevated ICP (with a cut-off often > 5.0-5.7 mm for ICP > 20 mmHg), studies investigating PDPH have paradoxically shown a reduction in ONSD post-spinal anesthesia, correlating with the ...