U.S., Feb. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07387419) titled 'Ultradian Steroid Rhythms in Adrenal Incidentalomas.' on Jan. 27.
Brief Summary: Twenty to 40% of adrenal incidentalomas are responsible for MACS (mild autonomous cortisol producing secretion). The biological tools used in current practice to explore MACS do not provide precise information on cortisol production abnormalities. This study is a comparative analysis of the dynamics/rhythmicity of interstitial cortisol and other steroid concentrations between MACS and non-secreting adenomas (ANS). Using the original and innovative U-RHYTHM system, interstitial fluid samples will be taken every 20 minutes for 24 to 48 hours from patients ...