U.S., Jan. 31 -- ClinicalTrials.gov registry received information related to the study (NCT07378930) titled 'ULTRA-high-risk Surveillance to Avoid Future Events: the ULTRA-SAFE Trial' on Jan. 23.
Brief Summary: The ULTRA-SAFE clinical trial is a prospective, randomized study designed to address the limitations of current "one-size-fits-all" colorectal cancer surveillance guidelines. While international standards recommend a three-year follow-up colonoscopy for all high-risk patients, data suggests that those with multiple advanced adenomas face a significantly higher recurrence risk (20%) compared to those with only low-risk adenomas (9%). To provide more personalized care, the trial compares a Standard Arm (colonoscopy at year three) agai...