Clinical Trial: UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis

U.S., Aug. 8 -- ClinicalTrials.gov registry received information related to the study (NCT07109986) titled 'UB-VV410 in Subjects With Active Refractory Systemic Lupus Erythematosus or Lupus Nephritis' on July 31.

Brief Summary: This is an open-label investigator-initiated trial (IIT) to assess the safety, efficacy, and PK/PD of UB-VV410 in adult subjects with clinically active treatment-refractory SLE. The study population will include subjects with active LN (as defined by evidence of active inflammation on renal biopsy, referred to as the LN cohort) and subjects with active SLE without LN (ie, non-LN SLE, referred to as the non-LN cohort). It is expected that the safety profile of UB-VV410 will be similar in subjects with active LN and s...