Clinical Trial: Treating Severe Mitral Valve Annular or Valvular Calcification Using Shockwave Balloon SMARTWAVE

U.S., May 1 -- ClinicalTrials.gov registry received information related to the study (NCT06952374) titled 'Treating Severe Mitral Valve Annular or Valvular Calcification Using Shockwave Balloon SMARTWAVE' on Feb. 06.

Brief Summary: Mitral stenosis (MS) is a heavily symptomatic valvular heart disease. Common causes of MS included chronic rheumatic heart disease (CRHD) and mitral annular calcification (MAC). Current guideline recommends percutaneous balloon mitral valvuloplasty (PBMV) being the first line intervention for rheumatic MS with favorable anatomy. However, severely calcified mitral valve (i.e. those with Wilkins scores>8) makes the mitral valve non-pliable and carries high risk of severe mitral regurgitation (MR) (4-19%) with conv...