U.S., Aug. 21 -- ClinicalTrials.gov registry received information related to the study (NCT07131969) titled 'Transcriptional Analysis of Mechanisms in Liver Failure and Sepsis' on Aug. 12.
Brief Summary: Context Acute liver failure (ALF) is a life-threatening condition that occurs on the background of a healthy liver. The most common cause of acute liver failure in the UK is paracetamol overdose. Acute liver failure results from liver damage and activation of the body's inflammatory defences with subsequent damage to other organs including kidneys, lungs and heart. This often requires life support in an intensive care unit before liver transplantation (LT), the only currently available and effective rescue treatment for acute liver failure...