U.S., Sept. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07197021) titled 'Transcatheter Edge-to-Edge Repair In Moderate and Exertional-Induced Severe MR (TIMER)' on Sept. 20.
Brief Summary: Transcatheter Edge-to-Edge Repair (TEER) has become an established alternative for the treatment of severe mitral regurgitation (MR). RESHAPE trial indicated that patients with moderate functional MR (FMR) and heart failure (HF) might benefit from TEER. However, it still not clear that TEER is effective for which subset of patients with FMR.
Hand-Gripping (HG), characterized with an increased venous return, preservation or increase of left ventricular (LV) afterload and systemic vascular resistance, has been identifi...