U.S., Sept. 17 -- ClinicalTrials.gov registry received information related to the study (NCT07174895) titled 'Tranexamic Acid and Drain Use in Knee Arthroplasty' on Aug. 30.
Brief Summary: This prospective randomized clinical study is designed to evaluate the effects of intra-articular tranexamic acid (TNA), with or without suction drainage, on perioperative blood management in patients undergoing total knee arthroplasty (TKA) for degenerative arthritis. A total of 192 patients will be randomly assigned to three groups: Group 1 will receive TNA with suction drainage, Group 2 will receive TNA only, and Group 3 will receive suction drainage only.
The primary outcomes will be total blood loss and transfusion requirements. Secondary outcomes ...