U.S., Aug. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07105618) titled 'Total Intravenous Anesthesia in Patients Undergoing Craniotomy' on July 08.

Brief Summary: Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.

Study Start Date: Sept., 2025

Study Type: INTERVENTIONAL

Condition: Anesthesia

Intervention: DRUG: Dexmedetomidine

Dexmedetomidine as an adjunct to total intravenous anesthesia.

DRUG: Fentanyl

Fentanyl as an adjunct to total intravenous anesthesia.

DRUG: Magnesium

Magnesium sulphate as an adjunct to total intrave...