U.S., Nov. 27 -- ClinicalTrials.gov registry received information related to the study (NCT07252115) titled 'TLSA Versus TBSA Surgical Approach for Hiatal Hernia With Gastroesophageal Reflux Disease' on Nov. 17.
Brief Summary: Gastroesophageal reflux disease (GERD), characterized by pathological reflux of gastric contents, affects 10%-20% of the global population with Western predominance and escalating incidence over recent decades. Anatomical and functional abnormalities of the esophagogastric junction (EGJ) such as hiatal hernia (HH) is one of the major pathophysiological mechanisms. GERD elevates risks for Barrett esophagus, esophageal adenocarcinoma and interstitial pulmonary fibrosis, while characteristic symptoms including reflux an...