U.S., Jan. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07319169) titled 'The Value of Spleen Stiffness Measurement in Patients With PBC' on Dec. 05, 2025.
Brief Summary: Recent evidence suggests that combining liver stiffness measurement (LSM) with spleen stiffness measurement (SSM) significantly improves risk stratification in patients with PBC. In a study the addition of spleen stiffness to liver stiffness enhanced the prediction of liver decompensation, providing a more precise evaluation of portal hypertension. Furthermore, when combined with platelet count, this approach effectively identified patients with a low probability of harboring HRVs. This could allow clinicians to safely avoid unnecessary e...