Clinical Trial: The Role of Endogenous Heparinization As an Intraoperative Predictive Marker for Postoperative ICU Admission

U.S., Jan. 30 -- ClinicalTrials.gov registry received information related to the study (NCT06799949) titled 'The Role of Endogenous Heparinization As an Intraoperative Predictive Marker for Postoperative ICU Admission' on Jan. 24.

Brief Summary: This prospective observational study investigates the role of endogenous heparinization as a predictive indicator for postoperative ICU admission. The phenomenon of endogenous heparinization is well described with a growing body of literature investigating its clinical significance. The mechanisms leading to the pathogenesis of endogenous heparinization are the following: 1) Liver insufficiency in clearing circulating glycosaminoglycans (GAGs) during acute liver failure, 2) Neutrophil-induced damag...