U.S., July 24 -- ClinicalTrials.gov registry received information related to the study (NCT07080411) titled 'the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal Cancer' on July 01.
Brief Summary: Based on preliminary findings on the motion error of the clinical target volume (CTV) in MR-guided adaptive radiotherapy (MRgART) for locally advanced rectal cancer (LARC), this study aims to reduce CTV-to-PTV margins and evaluate the complete response (CR) rate following MRgART in LARC patients. Additionally, it will investigate the safety and tolerability of MRgART, as well as its impact on:
3-year organ preservation rate
Local recurrence rate in patients under a "watch-and-wait" approach
3-year overall survival...