U.S., Aug. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07103564) titled 'The Effect of Local Melatonin Application Around Immediately Placed Implants in the Maxillary Premolar' on July 29.
Brief Summary: Background: Immediate implants provide ideal three-dimensional positioning compared to conventional implants. There may be a gap between the surface of the implant and the bone walls of the socket when it is inserted into a recently extracted alveolus. To compensate for this, various grafting materials are used. Recently, melatonin has gained significant attention because of its inhibitory action on bone resorption through upregulating the expression of osteoprotegerin, which acts as a decoy receptor for ...