U.S., Feb. 6 -- ClinicalTrials.gov registry received information related to the study (NCT06808841) titled 'Sufentanil in Patients With Lower Extremity Fracture Surgery Myocardial Damage Function Study' on Jan. 10.
Brief Summary: 1. To analyze the association of different doses of opioids on myocardial injury/protection through BMP-6/SMAD pathway.
2. To observe the effect of different doses of opioids on the expression of BMP-6 in bone marrow.
3. To investigate the relationship between different doses of opioids and BMP-6 and perioperative cardiovascular adverse events in patients with lower extremity fracture surgery.
Study Start Date: Feb. 05
Study Type: INTERVENTIONAL
Condition:
Myocardial Injury
Intervention:
DRUG: Sufentanil i...