Clinical Trial: Study to Identify Biomarkers of Oral Cavity Cancer Response to Neoadjuvant Immunotherapy Prior to Definitive Surgery

U.S., Jan. 16 -- ClinicalTrials.gov registry received information related to the study (NCT07343596) titled 'Study to Identify Biomarkers of Oral Cavity Cancer Response to Neoadjuvant Immunotherapy Prior to Definitive Surgery' on Jan. 06.

Brief Summary: The goal of this clinical trial is to study whether researchers can create a patient-specific tumor system, called a culture vessel, in a timely manner and determine if it can predict how someone will respond to a specific therapy.

Participants will:

* Undergo a research biopsy

* Take pembrolizumab per standard of care prior to surgery

Study Start Date: Jan., 2026

Study Type: INTERVENTIONAL

Condition: Oral Cavity Cancer

Intervention: BIOLOGICAL: Pembrolizumab

IV injection of pembr...