U.S., Dec. 30 -- ClinicalTrials.gov registry received information related to the study (NCT07307482) titled 'Study on the Mechanism of Gut Microbiota Mediating Restless Legs Syndrome Through Iron Metabolism' on Dec. 14.
Brief Summary: The goal of this observational study is to collect fecal and serum samples from patients with restless legs syndrome (RLS) and healthy controls for differential microbiota analysis to identify key bacterial species involved in the pathogenesis of RLS. Subsequently, metabolomic analysis will be performed on fecal and serum samples from RLS patients to identify key regulatory molecules in iron metabolism disorder pathways. Finally, correlation analysis will be used to determine which specific bacterial species ...