U.S., April 30 -- ClinicalTrials.gov registry received information related to the study (NCT06948656) titled 'Study of the Impact of HYPOglycaemia on Sarcopenia in CIRrhosis' on April 18.
Brief Summary: Fasting blood glucose is maintained by hepatic production of glucose from glycogenolysis or gluconeogenesis. In cirrhosis, glycogen storage capacity is reduced, with a consequent increase in gluconeogenesis to maintain blood glucose levels. Hypoglycaemia is particularly common during periods of prolonged nocturnal fasting. Cirrhosis can therefore be considered an 'accelerated fasting' disease. In a recent study, Honda et al. described 22% nocturnal hypoglycaemia in 105 patients analysed continuously. A previous study showed that the percent...